Thios. belongs to the same chemical group as Urea.
The colourless bitter crystals are soluble in water, alcohol, and ether. Thios. has been used externally and internally in cases of lupus, chronic glandular tumours, and for dissolving scar tissue; and internally for resolving tumours of the uterine appendages.
The usual internal dose in old-school practice is 4 to 8 grains once a day given hypodermically in a 15 per cent. solution. C. H. Pennoyer (quoted Pac. C. J. of H. viii. 199) relates this case:
Mrs. C., 69, had been several years ill with gastric distress, sciatica, pains in hips down to knees; SYMPTOMS.
Tinnitus caused by fibrous bands.
Stricture of rectum resolved.
Urine increased in quantity; no albumen or formed elements.
Tumours of uterine appendages.
Sensation of heat and burning in affected parts.─Bodily weight increased.─Glandular swellings reduced.
Distinct local reaction in lupus cases after a few hours.─Urticaria.─Lupus.─Scar tissues.
Reference: A Dictionary of Practical Materia Medica. J. H. Clarke.