The next that Hahnemann says on the dose is in the ” Medicine of Experience,” published in 1805, and in which he first announces the Homoeopathic law.
He says that if the remedy selected be the right one it will act in incredibly small doses. And again, if a small dose of diluted tincture of Opium is capable of removing sleepiness, the hundredth or even the thousandth part of the dose suffices as well.
In a paper published in 1808 he says that in certain bilious conditions ” a single drop of the tincture of Arnica root will often remove, in the course of a couple of hours, all the fever, all the bilious taste, all the tormina.”

In the first edition of the ” Organon,” published in 1810, he still recommends the smallest possible dose. He says :
“The smallest doses are equal to the disease !’ And again : “The dose must therefore be reduced to the smallest point capable of causing an aggravation of the symptoms, however slight ; such is the standard of measurement and incontrovertible axiom of experience.”
He does not mention the dynamization theory. The dose must be diminished to avoid aggravation. He uses the terms diminution, subdivision and, attenuation. He does not give the limit of his method of dilution. He says, however, that a dose divided and taken at intervals will act better than if taken at once, and that the power of the medicine is increased by being intimately mixed with a larger amount of fluid.
From the book Life and Letters of Dr. Samuel Hahnemann
by Thomas Lindsey Bradford.




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