The Arsenite of Quinine combines many of the properties of its two components, but having been proved it can be treated as a separate individuality.
The periodicity is intensified, and this is especially noted in the neuralgias. An irritable mood precedes the headache, which is reduced by mental and bodily exercise.
The gastralgia of Chi. ars. is pressure in solar plexus with tender spine just at back of it. Nausea and vomiting are followed by sleep. Bonino (H. R., iv 210), who gave it a prolonged proving, found the symptoms less at rest; in the morning; and when the stomach was empty. They were increased by motion (vertigo); and by eating (gastralgia).
The chief effects were manifested on the stomach, solar plexus, ligaments and skin. According to him it corresponds to tobacco intoxication and its effects; indigestion from unripe fruits; gastralgia from coarse food or ill-baked bread; chronic rheumatism of joints without swelling; tertiary syphilis of periosteum; colic from incarcerated flatus; intermittent fever with predominating chills, little thirst and continuous almost convulsive yawning; effects of severe and depressing influences on the mind; to convalescence from long-lasting sickness. The circulation was slow, and limbs relaxed. Weakness, prostration, and disinclination for mental exertion were marked in several provers.
Dislike of mental occupation in spite of clear-headed lightness about head and feeling of exhilaration.─Memory impaired.─Anxiety.─Child sits up in bed lamenting.─Irritable mood precedes headache.
Sudden attacks of vertigo, erect position and out of doors.─Post-nasal catarrh by eating, for a few moments; repeated several mornings.─Contracting gastralgia, as if pushed up; > only for a moment by tasteless eructation.
Pain in epigastrium as from foul stomach.─Pain as from flatus wedged into flexure of colon.─Aching around navel and in ilium.─In evening severe colicky pains > by pressure.
Violent urging to stool, evacuated in prolonged rush till bowel empty; stool thin, brown, painless.─Diarrhœa, morning, hardly had time to dress, brown, liquid with jelly-like lumps: pain in l. iliac region, quite severe when walking.─Towards morning, frequent, bad-smelling flatus.─Stool pappy; watery, fetid.─Stool, fecal, with mucus and blood, preceded and followed by tenesmus.─Stool hard, voided with difficulty; aided by pressing finger on coccyx.─Could eat no breakfast, but took some dinner, and immediately thereafter great urging to stool, which was watery and blackish; some pain in hypogastrium.
Urine scanty; frequent urging.─Urine increased, urging tiresome.
A peculiar burning ache about sphincter vesicæ and throughout urethra.
Breathing unsatisfactory, wants more air than he can take into his lungs.─Respiration very free, as if thorax were hollow.─Suffocative attacks beginning in morning and lasting till noon; > sitting bent forward at open window, walking.─Pressure on tuberosity of tibia, which is somewhat swollen.─Pain in r. knee as from a fall.─Cramp in calf.─Pains back of r. thigh and in calf.─Numbness of legs after hardly having lain down.─Weakness of lower limbs.
In different parts of body burning fluttering beats, as from electricity.─Stiffness of all bones, even while walking.─Burning pains deep in joints.─Burning pains as in periosteum.─Nervous restlessness, unable to remain in the house.─While walking, dizziness and collapse.─Desire to lie down.─Complete relaxation of muscles as from tobacco-poisoning.
Goose flesh, esp. of lower extremities.─Periodical furuncles, which relieve the head.─Burning, erysipelatous redness and violent itching by cold.
Night full of visions; heavy sleep till morning.─Nervous restlessness, anxious dreams.─Sleep frequently interrupted.
General chill and cold.─After the feverish cough in the chill, no reaction of warmth.─Flying heat with nausea.─Cold, clammy sweat.
Reference: The Dictionary of Practical Materia Medica. J. H. Clarke